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samueladjei

 

Name: Dr. Samuel K.Adjei
Email:sadjei@noguchi.ug.edu.gh
Telephone:+233-302-501178/9 ext 3401

Department: Animal Experimentation

Administrative Role: Head of Department

Dr. Samuel Adjei earned BSc. (Hons) in Biological Sciences in 1992 from the Kwame Nkrumah University of Science and Technology (KNUST). In 2002, he proceeded to undertake further studies in Nagoya University, Japan where he obtained MSc.and PhD degrees in Applied Molecular Bioscience (Animal Genetics) in 2004 and 2007, respectively.

In 2008, he became a Research Fellow in the Department of Animal Experimentation. Prior to this, he worked as a Research Assistant and assisted in the establishment of well-defined laboratory animals for biomedical research and the development of the grasscutter as a model animal for buruli ulcer research. He has taught Biology at the Advanced and Senior High School Levels for several years and is also a Part-time lecturer in Principles of Genetics (Level 300) and Advanced Genetics (Level 400) in the Department of Animal Biology and Conservation Science, School of Biological Sciences, College of Basic and Applied Sciences, University of Ghana. His specialty training encompasses Laboratory Animal Science (Breeding and quality assurance), Avian influenza molecular diagnostics, and Medical and Experimental Mammalian Genetics. Since 2009 he has collaborated with other researchers and has won several research grants.

Research Interests:
  • Laboratory Animal Science and Technology, model animal development and establishment of well-defined animals for biomedical research
  • Phytotherapy and drug development; In vivo evaluation/characterization of some tropical medicinal plants
  • Medical and experimental mammalian genetics with special interest in uterine leiomyoma (Fibroids) and benign prostate hyperplasia (BPH) studies.

Projects:

  1. Anticonvulsant activity-guided fractionation of Synedrellanodiflora(l) Gaertn whole plant extract. Building Stronger Universities Initiative Platform on Human Health (BSU-PHH), College of Health Sciences, University of Ghana. Role: Co-PI
  2. Investigation into anti-asthmatic potential of regular consumption of natural cocoa powder in ovalbumin or IgE sensitized guinea-pigs. Building Stronger Universities Initiative Platform on Human Health (BSU-PHH), College of Health Sciences, University of Ghana. Role: Co-PI.
  3. Screening Ghanaian medicinal plants for antipsychosis properties. University of Ghana Research Grant. Role: Co-PI.
  4. Collaborator: Observational study: the effect of the aqueous root extract of Croton membranaceus on the treatment of Benign Prostate Hyperplasia and Prostate Cancer. University of Ghana Research Grant. Role: Collaborator.

  5. Intra-ACP Academic mobility scheme project title Enhancing community of practice in one health for infectious diseases through postgraduate training. European Commission – Africa, Caribbean and Pacific (ACP) - Education, Audiovisual and Culture Executive Agency funded project worth 2,000,000.00. Role: Member of Ghanaian team.

  6. Pharmacological study of the antinociceptive effect of Synedrellanodiplora in neuropathic pain. IFS grant. Role: Co-PI.

  7. Developing an alternate anti-epileptic product from medicinal plants: exemplifying utilization of natural resources for quality health. University of Ghana Research Grant. Role: Co-PI.

  8. National Research Network Biomed (NRN Biomed) One Health Ghana Consortium. ACP-EU Grant for enhanced research into infectious diseases. Role:Member, Coordinating Team

  9. University of Ghana Grant for research into the effect of some tropical medicinal plants on prostate and uterine leiomyoma. Role: Co-PI.

 

Recent Publications:

  1. Patrick Amoateng, Samuel Adjei, Dorcas Osei-safo, Kennedy K. E. Kukuia, Emelia Oppong Bekoe, Thomas K. Karikari, and Samuel B. Kombian. Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis. BMC Complementary and Alternative Medicine 17:389 DOI 10.1186/s12906-017-1901-2 (2017).
  2. Patrick Amoateng, Samuel Adjei, Dorcas Osei-Safo, Kennedy K.E. Kukuia, Thomas K. Karikari and Alexander K. Nyarko. An ethanolic extract of Desmodium adscendens exhibits antipsychotic-like activity in mice. J Basic Clin Physiol Pharmacol; DOI 10.1515/jbcpp-2016-0115 (2017).
  3. Patrick Amoateng, Samuel Adjei, Dorcas Osei‑Safo, Kennedy Kwami Edem Kukuia, Irene Akwo Kretchy, Joseph Adusei Sarkodie, Benoit Banga N’Guessan. Analgesic effects of a hydro‑ethanolic whole plant extract of Synedrella nodiflora (L.) Gaertn in paclitaxel‑induced neuropathic pain
  4. in rats. BMC Res Notes 10:226 DOI 10.1186/s13104-017-255 1-7 (2017).
  5. George Awuku Asare, Robert A. Ngala, Daniel Afriyie, Samuel Adjei, Adriana Nyarko, Yvonne Anang-Quartey, Bernice Asiedu, Derek Doku, Brodrick Y. Amoah, Kennedy Bentum, Iddi Musah, Kensese Mossanda. Calcium - Magnesium imbalance implicated in benign prostatic hyperplasia and restoration by a phytotherapeutic drug – Croton membranaceus Müll.Arg. BMC Complementary and Alternative Medicine 17:152 DOI 10.1186/s12906-017-1663-x (2017).
  6. 5.Patrick Amoateng, Samuel Adjei, Dorcas Osei-Safo, Believe Ahedor, Seidu A. Mahmood, Benoit B. N’guessan, Isaac J. Asiedu-Gyekye, Alexander K. Nyarko. Long-term continuous administration of a hydro-ethanolic extract of Synedrella nodiflora (L) Gaertn in male Sprague-Dawley rats: biochemical, haematological and histopathological changes. Ghana Med. J.; 50(3): 163-171 (2016).
  7. 6.Isaac Julius Asiedu-Gyekye, Mahmood Abdulai Seidu, Banga Benoit Nguessan, Samuel FrimpongManso, Joseph Edusei Sarkodie, Samuel Adjei, Schevadnazy Kutu, Joseph Osei-Little1, Alexander Kwadwo Nyarko and Philip Debrah. A dietary strategy for the management of artemether-lumefantrine-induced cardiovascular and renal toxicity. BMC Complementary and Alternative .Medicine 16:348, http://dx.doi.org/10.1155/2016/7387286 (2016)
  8. Philip Debrah, Henry Nettey, Katja Kjeldgaard Miltersen, Patrick Ayeh-Kumi, Birgitte Brock, Joseph Adusei Sarkodie, Irene Akwo-Kretchy, Patrick Owusu-Danso, Samuel Adjei, Eskild Petersen and Tore Forsingdal Hardlei. Artemether–Lumefantrine Concentrations in Tablets and Powders from Ghana Measured by a New High-Performance Liquid Chromatography Method. Am J Trop Med Hyg. 95:158-163, (2016).
  9. Isaac Julius Asiedu-Gyekye,1 Kennedy Kwami Edem Kukuia, AbdulaiMahmood Seidu, Charles Antwi-Boasiako, Benoit Banga N’guessan, Samuel Frimpong-Manso, Samuel Adjei, Jonathan Zobi,
  10. Abraham Terkpertey Tettey,1 and Alexander Kwadwo Nyarko. Unsweetened Natural Cocoa Powder Has the Potential to Attenuate High Dose Artemether-Lumefantrine-Induced Hepatotoxicity in Non-Malarious Guinea Pigs. Evidence-Based Complementary and Alternative Medicine Volume 2016, Article ID 7387286, 11 pages http://dx.doi.org/10.1155/2016/7387286 (2016).
  11. George Awuku Asare, Samuel Adjei, Daniel Afriyie, AKua Bempomaa, Appiah-Danquah, Jonas Asia, Bernice Asiedu, Sheila Santa and Derek Doku. Croton membranaceus Improves Some Biomarkers of Cardiovascular Disease and Diabetes in Genetic Animal Models. Journal of Clinical and Diagnostic Research, 9 (12), OF1 ~ OF5, 2015
  12. 10.Asare GA, Afriyie D, Ngala RA, Annan Y, Appiah AA, Musah X, Adjei S, Bamfo KB, Sule SD, Gyan BA, Edoh DA. Shrinkage of Prostate and Improved Quality of Life: Management of BPH Patients with Croton membranaceus Ethanolic Root Extract. Evidence-based Complementary and Alternative Medicine 02/2015; DOI: 10.1155/2015/365205


 

 

 

 

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